This news article landed in my inbox via a Facebook group. Thought it might be of interest. I remember reading a lot about 4AP a while ago with mixed results. This new development sounds very promising.
"For the first time, 4-aminopyridine-3-methanol is shown to restore function in chronic spinal cord injuries," he says. "It also reduces neuropathic pain to a greater degree than 4-AP.
"Because persistent chronic pain is a serious problem among patients with spinal cord injuries, 4-aminopyridine-3-methanol could potentially be used to reduce pain, independent of any motor benefits."
Interesting. I don't know how to determine if one's spinal chord damage is caused by myelin damage or another mechanism. Also don't see info on how the drug is administered.
I'm all in for treatments that may increase function as long as there is ZERO chance of degrading my current status (i.e. no additional loss of function, no increase in nerve pain, no increase in spasm).