I did have a huge spike in calcium at one point which was spinal cord injury related. It happened because the calcium from my bones started leeching into my blood which happened since my body no longer needed all that calcium because I wasn't load bearing. I was actually on an IV at the time to stabilize my blood calcium level.
The only issues I have had with vitamin/nutrients is my Vitamin D levels. Pretty hard to get sun in the winter. I had problems with my potassium after my first surgery but it was related to the infection I got.